Common Signs of Illness in Cats: When to See a Vet

If your cat is having trouble breathing, has collapsed, is straining to urinate with little or no output, is having a seizure, has been in an accident or fall, is bleeding heavily, or may have eaten something toxic (including lilies, which are highly toxic to cats), stop reading and contact an emergency veterinary clinic now. For suspected poisoning, the ASPCA Animal Poison Control Center (U.S.) can be reached at (888) 426-4435 (a consultation fee may apply).

For everything else, this guide organizes common warning signs by urgency. It's general information, not a diagnosis — a symptom below is a reason to get your cat checked, never a confirmation of a specific condition. That distinction matters even more with cats than with dogs, for a reason worth understanding first.

Common Signs of Illness in Cats
Photo by Asabae2752, CC BY-SA 4.0, via Wikimedia Commons.

Veterinary disclaimer. This article is general, informational content. It doesn't diagnose your pet's condition and doesn't replace an in-person veterinary exam. See the full Veterinary Disclaimer.

Why cats are harder to read than dogs

Cats are much better than dogs at masking discomfort. According to Dr. Stacy Eckman of Texas A&M's College of Veterinary Medicine, this is believed to be a survival instinct: in the wild, an animal that visibly shows weakness is more vulnerable to predators, and that instinct persists in domestic cats. In practice, this means many cats don't show obvious pain or distress until a problem is fairly advanced — which is exactly why subtle behavior changes deserve more attention in cats than they might in dogs, and why routine annual (or more frequent, for older cats) veterinary visits matter even when a cat seems fine.

Urgent: contact an emergency vet now

SignWhy it's urgent
Difficulty breathing, open-mouth breathing, or blue/pale gumsCats rarely pant like dogs do; labored breathing is a serious sign
Straining in the litter box with little or no urine, especially in male catsCan indicate a urinary blockage — a true emergency that can be fatal within 24–48 hours if untreated
Collapse, extreme lethargy, or inability to standCan indicate a range of serious underlying issues
Seizures, or repeated seizuresNeeds prompt evaluation
Not eating or drinking at all for more than 24 hoursCats that stop eating are at risk of a serious liver condition (hepatic lipidosis) that can develop quickly
Suspected ingestion of a toxin, including lily plants (all parts, including pollen and vase water, are highly toxic to cats)Some toxins cause organ damage within hours
Persistent vomiting or diarrhea unresolved after 12–24 hoursCats dehydrate and decline faster than dogs relative to their size
Sudden hind-limb weakness or paralysis, or extreme pain vocalizationCan indicate a cardiac or vascular emergency

Soon: book an appointment in the next day or two

These are subtle behavior changes that Texas A&M's guidance identifies as the kind of signs an owner is most likely to miss, precisely because cats hide illness so well:

Worth mentioning at your next routine visit

Why routine vet visits matter for cats specifically

Because cats are so good at masking symptoms, annual wellness exams (and more frequent visits for senior cats) are one of the only reliable ways to catch problems early. During a routine exam, a veterinarian can pick up on weight changes, subtle findings on a physical exam, and recommend bloodwork as your cat ages — catching things well before they'd be obvious at home. This is a case where "my cat seems totally fine" isn't the same as "my cat has no health issues."

FAQ

My cat has always been shy and hides a lot — how do I know if new hiding is a health issue? The key is a change from your cat's individual baseline. A naturally shy cat hiding in a familiar spot during a loud event is different from a normally social cat suddenly avoiding people and staying in one spot for most of the day. If you're unsure, a call to your vet's office to describe the change is a reasonable next step.

Is it normal for cats to throw up hairballs sometimes? Occasional hairballs can be normal, but frequent vomiting (more than once every week or two), or vomiting combined with weight loss or appetite changes, is not something to assume is "just hairballs" — it's worth a vet visit.

Veterinary disclaimer: This article is for general educational purposes only and is not a substitute for professional veterinary diagnosis, examination, or treatment. It cannot tell you what's wrong with your specific cat. If your cat is showing any of the urgent signs listed above, contact an emergency veterinarian immediately rather than relying on this or any other article.

Sources

  1. Texas A&M College of Veterinary Medicine — When Is Your Cat Hiding Illness or Injury?
  2. Texas A&M College of Veterinary Medicine — Recognizing a Pet Emergency
  3. ASPCA — Animal Poison Control Center

Sources verified during editorial review, September 2026.

Alex Morgan

Writer, TrundlePaw — this article was not reviewed by a licensed veterinarian.

Alex Morgan writes and edits TrundlePaw's guides, researching each piece from the primary sources listed at the end of the article. Alex is not a veterinarian, certified trainer, or nutrition professional — health and behavior content is written from published veterinary and animal-welfare sources, not personal or professional clinical experience, and isn't a substitute for individualized advice from a licensed professional who can examine your pet.